Programme led by

Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin 2, Ireland

Gianpiero Cavalleri

SFI Centre: FutureNeuro
RCSI - University of Medicine and Health Sciences

Domain / Application Expertise


Gianpiero is particularly interested in working with Fellows on projects related to genomics of disease predisposition, pharmacogenomics, digital health and population genetics. His research group works on diverse topics at the interface of computational biology, clinical research and human evolution. His team are applying the latest generation of DNA sequencing techniques to identify novel genetic causes of epileptic encephalopathies and improve the diagnostic yield of genetic sequencing in the neurology clinic. His portfolio includes significant existing industry collaboration through the BESTS project and opportunities for PhD supervision through a National Centre for Research Training on in Genomics Data Science.

Gianpiero received his PhD in human genetics at University College London in 2006. Prior to his arrival at RCSI, he worked at the Institute for Genome Science and Policy at Duke University, North Carolina. He was appointed to faculty at RCSI in 2008. Prof. Cavalleri has published over 150 articles in leading peer-reviewed international journals including NatureNature GeneticsPNAS and the New England Journal of Medicine. His key scientific discoveries include the identification of one of the strongest signatures of natural selection detected in the human genome to date, characterizing genetic predictors of cutaneous adverse reactions to anti-epileptic drugs and describing fine-scale population structure across the island of Ireland, and within the indigenous Irish Traveller community.

Research Keywords
Bioinformatics, Genetics, Population Genetics, Digital Health, Neuroscience, Neurogenetic disorders